Vascular Disease

Vascular disease refers to diseases of the heart and blood vessels located throughout the body. The most common cause of vascular disease is atherosclerosis. Atherosclerosis is a progressive, degenerative condition in which plaque, consisting of lipids, cholesterol, calcium and other substances found in the blood stream, accumulates on the vascular wall. Plaque occurs in several different forms and may be located throughout the vascular system. Plaque varies in composition, with portions that are hard and brittle, referred to as calcified plaque, and other portions that are fatty or fibrous. Endovascular treatments for atherosclerosis are performed in a catheterization laboratory located in an OBL or hospital. These patients are diagnosed by their primary care physician, podiatrist, or other specialist, and then treatment is performed by an interventional cardiologist, interventional radiologist, or vascular surgeon.

Peripheral artery disease (PAD) is atherosclerosis of the extremities, most commonly in the legs. Smoking, genetic predisposition, diabetes, aging, and obesity may significantly increase the risk of developing PAD. Plaque build-up reduces blood-flow to the surrounding tissue, causing claudication, pain or cramping in the leg, the most common early symptoms of PAD. Symptoms may progress to include numbness, tingling or weakness in the leg and, in severe cases, burning or aching pain in the foot or toes.

As PAD progresses, additional symptoms may develop on the legs, including cooling, color changes, or sores that do not heal. If untreated, PAD can lead to critical limb ischemia (CLI), a condition where there is not enough oxygenated blood being delivered to the limb to keep the tissue alive.

As of June 2017, the SAGE Group reported that conservatively 22 to 30 million people suffer from CLI worldwide. If untreated, CLI may result in ulceration, infection, or gangrene in the feet and legs and eventually limb amputation or death.


DABRA is a minimally-invasive laser and disposable catheter system that is used by physicians as a tool in the endovascular treatment of vascular blockages resulting from lower extremity vascular disease, a form of PAD. It uses 308 nm ultraviolet light to break plaque down into its fundamental chemistry such as proteins, lipids, minerals, and water, eliminating blockages by essentially dissolving them without generating potentially harmful particulates.


Coverage may vary according to patients’ individual plans. Talk to your physician’s billing staff for details about your insurance coverage.

DABRA Vascular Testimonials

Dr Mahmud

Ehtisham Mahmud

When it comes to total occlusion, normally if you can’t cross with a guidewire, you can’t do it. With DABRA, we were able to stay within the true lumen and recanalize without a wire in front.


UC San Diego Cardiovascular Clinic

Marzia Lugli

Marzia Lugli

It’s very easy, very simple, very trackable, and I did not encounter any problems in the technique. It is really simple and very safe.

MD - Hesperia Hospital Mendona